Bioengineering, Cell therapy and Surgery in Congenital Malformations

17
Publications
17.6
%
%Q1
44
Citations
85
%
% Open Access
7
Ongoing Projects
4
Presented Theses
12
Active Clinical Trials

The group of Bioengineering, Cell therapy and Surgery in Congenital Malformations has been peformimg research focused in the research lines of congenital malformations, sucha as spina bifida and congenital diaphragmatic hernia, as well as in musculoskeletal and osteoarticular pathologies. The group has received national and international funding for the development of research activities and different studies has been published in national and international journals.

eCOREs

  • Global Health
  • Woman & Child Health & Rare Diseases
  • Brain & Mind and Behaviour
  • Advanced Therapies and Advanced Interventions, Nanomedicine, Transplant & Donation

Team

Group Leader
Manuel López Paredes

Principal Investigator (PI)
Carles Giné Prades, Francisco Soldado Carrera, Mario Marotta Baleriola, Héctor Boix Alonso

Researchers
José Andrés Molino Gahete, Gloria Fatou Royo Gomes, José Luis Peiró Ibáñez, Josep Maria de Bergua Domingo, Marino Asensio Llorente, Jorge Knörr Giménez

PhD Students
Laura Vidal Fornells, Ingrid Vila Fernández

Lab Technicians
Anabel Sacristán Ruiz, Pamela Dominguez Baez, Laura Lozano Marcó

Selected Publications

Molino, Jose Andres, Hidalgo, Ernest, Quintero, Jesus, Coma, Ana, Ortega, Juan, Juamperez, Javier, Mercadal-Hally, Maria, Riera, Lluis, Riaza, Lucia, Bilbao, Itxarone et al.
Delayed sequential abdominal wall closure in pediatric liver transplantation to overcome “large for size” scenarios.
Pediatr Transplant. 2022 Feb;26(1):e14132.
DOI: doi: 10.1111/petr.14132.
IF: 1.502

Gander, Romy, Asensio, Marino, Royo, Gloria Fatou, Lopez, Manuel et al.
Pediatric laparoscopic mitrofanoff procedure- preliminary results of a simplified technique.
J Pediatr Urol. 2022 Apr;18(2):112.e1-112.e7.
DOI: doi: 10.1016/j.jpurol.2021.12.018. Epub 2022 Jan 7.
IF: 1.83

Guillen, G, Hladun, R, Martos, M, Cano, P, Molino, J A, Lopez-Fernandez, S, Lopez, M et al.
Minimally invasive surgery for pediatric dumbbell neuroblastoma: systematic literature review and report of a single-stage neurosurgical and thoracoscopic approach.
Clin Transl Oncol. 2022 May;24(5):950-957.
DOI: doi: 10.1007/s12094-021-02724-4. Epub 2021 Oct 30.
IF: 3.405

Gander, Romy; Asensio, Marino; Andres Molino, Jose; Fatou Royo, Gloria; Lopez-Gonzalez, Mercedes; Perez, Victor; Lopez, Manuel; Ariceta, Gema et al.
Pediatric kidney retransplantation focused on surgical outcomes.
J Pediatr Urol. 2022 Jun 25. pii: S1477-5131(22)00288-1.
DOI: doi: 10.1016/j.jpurol.2022.06.019.
IF: 1.83

Knorr, Jorge; Soldado, Francisco; Violas, Philippe; Sanchez-Alvarez, Mikel; Domenech, Pedro; de Gauzy, Jerome Sales et al.
Treatment of hallux valgus in children and adolescents.
Orthop Traumatol Surg Res. 2022 Feb;108(1S):103168.
DOI: doi: 10.1016/j.otsr.2021.103168. Epub 2021 Dec 3.
IF: 2.256

Selected Projects

nTRACK: Multimodal nanoparticles for structural and functional tracking of stem cell therapy on muscle regeneration..
Principal Investigator: José Raul Herance Camacho
Agency: EUROPEAN COMMISSION
Funding: 1,019,687.5 €
Period: 2017-2022

Teràpia cel·lular i cirurgia en malformacions congènites
Principal Investigator: Manuel López Paredes
Agency: AGAUR
Funding: 0.01
Period: 2022-2024

ALBINO: Effect of ALlopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome
Principal Investigator: Héctor Boix Alonso
Agency: EUROPEAN COMMISSION
Funding: 0.01
Period: 2017-2022

Terapia celular para la regeneración neutral y el tratamiento del mielomeningocele en modelo experimental de feto de oveja.
Principal Investigator: Carlos Giné Prades
Agency: Instituto de Salud Carlos III
Funding: 83,490 €
Period: 2019-2023

Investigación industrial de nuevas tecnologías para el tratamiento personalizado de patologías osteoarticulares de rodilla a través de Inteligencia Artificial e implantes celularizados generados mediante bioimpresión 3D (BioprintIA)
Principal Investigator: Francisco Soldado Carrera
Agency: CENTRO PARA EL DESARROLLO TÉCNICO INDUSTRIAL (CDTI)
Funding: 153,300 €
Period: 2020-2023

Patents

METHOD TO PREDICT THE LACK OF RESPONSE TO ANTI-TNF ALPHA THERAPIES
Priority Number: PCT/EP2014/066604 (US)
Priority Date: 1/08/2014
Applicants: 66% VHIR, 33,3 % H. Clínic

RISK LOCUS FOR PSORIATIC ARTHRITIS
Priority Number: 62/151,952 (PCT)
Priority Date: 23/04/2015
Applicants: VHIR, CLINIC, IGTP

METHOD TO PREDICT RESPONSE TO TREATMENT WITH ANTI-TNF ALPHA AGENTS
Priority Number: EP14179452.9 (PCT)
Priority Date: 1/08/2014
Applicants: VHIR

Pronóstico de respuesta al tratamiento con anti-TNFalfa en pacientes de artritis reumatoide
Priority Number: P201330650 (PCT)
Priority Date: 3/05/2013

METODO IN VITRO Y KIT PARA EL PRONOSTICO O PREDICCION DE LA RESPUESTA POR PARTE DE PACIENTES CON ARTRITIS REUMATOIDE AL TRATAMIENTO CON AGENTES BLOQUEANTES DEL FACTOR TNF alfa (INFLIXIMAB)
Priority Number: P200802713 (ES)
Priority Date: 24/09/2008
Applicants: VHIR

Selected Dissemination Activities

IV Curso de NEUROLOGÍA PEDIÁTRICA: La prevención como piedra angular en enfermedades neurológicas de la infancia
Place: Vall d’Hebron University Hospital (Barcelona)
Date: 17/10/2024 – 18/10/2024
Researchers from our group discussed the state of hospital care and research in relation to the prevention of paediatric neurological diseases

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Reunión de familias con Distonía Mioclónica y otras distonías (tercera edición)
Place: Vall d’Hebron University Hospital (Barcelona)
Date: 13/06/2024
Researchers from our group, in collaboration with the Dystonia Patient Association, presented recent advances in both clinical care and research aimed at improving the treatment and management of dystonia

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International Congress of Parkinson’’s Disease and Movement Disorders 2024.
Place: Philapdelphia, USA.
Date: 27/09/2024-01/10/2024
Belén Pérez, the group leader, presented the following talk: The Spectrum of Cerebral Palsy: From Perinatal Brain Injury to Genetic.

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XLVI SENEP Anual Meeting
Place: Valladolid, Spain
Date: 23/05/20254-25/05/2024
Belén Pérez, the group leader, presented the following talk: Movement disorders as diagnostic clues to treatable pathologies.

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World Muscle Society Congress 2024
Place: Prague (Czech Republic)
Date: 08/10/2024-12/10/2024
David Gómez presented the following poster: Different lower limb muscle MRI patterns in autosomal dominant titinopathies

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